Protein design: Past, present, and future.
نویسندگان
چکیده
Building on the pioneering work of Ho and DeGrado (J Am Chem Soc 1987, 109, 6751-6758) in the late 1980s, protein design approaches have revealed many fundamental features of protein structure and stability. We are now in the era that the early work presaged - the design of new proteins with practical applications and uses. Here we briefly survey some past milestones in protein design, in addition to highlighting recent progress and future aspirations.
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ورودعنوان ژورنال:
- Biopolymers
دوره 104 4 شماره
صفحات -
تاریخ انتشار 2015